Cilostazol: What It Is and How It Works

If your doctor mentioned cilostazol, they’re probably talking about a pill that helps improve blood flow in the legs. It’s approved mainly for peripheral artery disease (PAD), which means narrowed arteries that make walking painful or difficult. Cilostazol works by blocking an enzyme called phosphodiesterase III; this relaxes blood vessels and stops platelets from clumping together, so more oxygen reaches your muscles.

Dosage and Administration

The usual dose is 100 mg taken twice a day, about half an hour before breakfast and dinner. Swallow the tablets whole—don’t crush or chew them. If you miss a dose, take it as soon as you remember, but if it’s almost time for your next dose, just skip the missed one. Don’t double up; that can raise the risk of side effects.

People with severe liver problems should avoid cilostazol because the drug is processed in the liver. Also, if you’re under 18 or pregnant, this medication isn’t recommended. Always tell your pharmacist about other medicines you use, especially anticoagulants, certain antibiotics, and some heart drugs, because they can interact.

Common Side Effects & Safety Tips

Most folks feel fine, but a few notice headaches, dizziness, or an upset stomach. Some report swelling in the ankles or a rapid heartbeat—if those happen, call your doctor right away. Rarely, cilostazol can cause serious issues like bleeding or severe allergic reactions; watch for unusual bruising, coughing up blood, or skin rash.

To keep side effects low, stay hydrated, eat balanced meals, and avoid alcohol in excess. If you’re on a low‑sodium diet, check the pill’s label—some formulations contain small amounts of sodium. Keep a short journal of any new symptoms; it helps your doctor decide if the dose needs adjusting.

In summary, cilostazol can be a game‑changer for walking pain caused by PAD when used correctly. Follow the dosing schedule, report any odd feelings promptly, and keep an eye on drug interactions. With these simple steps, you’ll get the most benefit while staying safe.